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KMID : 1037420070020020079
Journal of Korean Skull Base Society
2007 Volume.2 No. 2 p.79 ~ p.82
A Case of Endoscope assisted Endonasal Transsphenoidal Surgery for Follicle-stimulating hormone-secreting Pituitary Adenoma
Chung Jong-Chul

Kim Seung-Min
Jung Sung-Sam
Chung Seung-Young
Kim Byung-Joon
Abstract
Follicle-stimulating hormone-secreting pituitary adenomas are rarley diagnosed and likely considered as a non-functioning pituitary tumor. Because they usually do not present until of sufficient size to cause neurologic deficits by mass effect or hypopituitarism, whereas other functioning tumors - acromegaly, prolactinoma, Cushing¡¯s disease - requently present earlier with symptoms caused by physiologic effects of excess hormones that they secrete. 62-year-old man suffered from visual disturbance. Endocrinologic evaluation showed high serum FSH level. Suprasellar extended pituitary mass with compression to optic chiasm & cavernous sinus was imaged on MRI and removed by endoscope assisted endonasal transsphenoidal surgery. It was composed of gonadotroph showed strong immunohistochemical reactivity against FSH and LH. Uncommon pituitary tumors such as FSH-secreting adenomas can be defined early and accurately through correlation between their clinical, endocrionological, radiographic and immunohistochemical characteristics.
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